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This schedule indicates the recommended ages for routine administration
of currently licensed childhood vaccines as of 11/1/99.
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Infants born to HBsAg-negative mothers should receive the 1st dose of
hepatitis B (Hep B) vaccine by age 2 months. The 2nd dose should be at least
one month after the 1st dose. The 3rd dose should be administered at least 4
months after the 1st dose and at least 2 months after the 2nd dose, but not
before 6 months of age for infants.
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Infants born to HBsAg-positive mothers should receive hepatitis B
vaccine and 0.5 ml, hepatitis B immune globulin (HBIG) within 12 hours of
birth at separate sites. The 2nd dose is recommended at 1 month of age and
the 3rd dose at 6 months of age.
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Infants born to mothers whose HBsAg status is unknown should receive
hepatitis B vaccine within 12 hours of birth. Maternal blood should be drawn
at the time of delivery to determine the mother's HBsAg status; if the HBsAg
test is positive, the infant should receive should receive HBIG as soon as
possible (no later than 1 week of age). All children and adolescents
(through 18 years of age) who have not been immunized against hepatitis B
may begin the series during any visit. Special efforts should be made to
immunize children who were born in or whose parents were born in areas of
the world, with moderate or high endemicity of hepatitis B virus infection.
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The 4th dose of DTAP (diphtheria and tetanus toxoids and acellular
pertussis vaccine) may be administered as early as 12 months of age,
provided 6 months have elapsed since the 3rd dose and the child is unlikely
to return at age 15-18 months. Td (tetanus and dephtheria toxoids) is
recommended at 11-12 years of age if at least 5 years have elapsed since the
last dose of DTP, DTAP or DT. Subsequent routine Td boosters are recommended
every 10 years.
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Three Haemophilis influenzae type b (Hib) conjugate vaccines are
licensed for infant use. If PRP-OMP (PedvaxtHIB, or Com Vax, (Merick) is
administered at 2 and 4 months of age, a dose at 6 months is not required.
Because clinical studies in infants have demonstrated that using some
combination products may induce a lower immune response to the Hib vaccine
component, DTaP/Hib combination products should not be used for primary
immunization in infants at 2, 4, or 6 months of age, unless FDA-approved for
these ages.
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To eliminate the risk of vaccine-associated paralytic polio ( VAPP ), an
all-IPV schedule is now recommended for routine childhood polio vaccination
in the United States. All children should receive four doses of IPV at 2
months, 4 months, 6-18 months, and 4-6 years.
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The 2nd dose of measles, mumps, and rubella (MMR) vaccine is recommended
routinely at 4-6 years of age but may be administered during any visit,
provided at least 4 weeks have elapsed since receipt of the 1st dose and
that both doses are administered beginning at or after 12 months of age.
Those who have not previously received the second dose should complete the
schedule by the 11-12 Year old visit.
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Varicella (Var) vaccine is recommended at any visit on or after the
first birthday for susceptible children, i.e. those who lack a reliable
history of chickenpox (as judged by a health care provider) and who have not
been immunized. Susceptible persons 13 years of age or older should receive
2 doses, given at least 4 weeks apart.
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Hepatitis A (Hep A) is recommended for use in selected states and/or
regions; consult your local public health authority. New Jersey is not a
selected state for routine vaccination of Hepatitis A.
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